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by CMN Lopes · 2015 — molecular pathways, which were efficient per se in delaying disease phenotype, ... A doença de Huntington (DH) é uma doença genética, autossomica dominante​, causada ... mutante caracterizámos o papel de HTT humana na orientação do fuso mitótico em ... Stojkovic, M., M. Lako, T. Strachan and A. Murdoch (2004).. by WH Hurk · 2001 — Molecular and cell biological aspects of Alzheimer's Я-amyloid precursor and related ... affected in AD (for example, CA1 and subiculum in the hippocampus; Strachan et al.,. 1997). The DS patients ... 1-18: Humana Press, Totowa, NJ. 148 ... genetica, cluster paraklinische specialismen van het Universitair Medisch. Centrum ...